Alexei Y. Kostygov

ResearcherID: https://publons.com/researcher/D-3931-2015
Scopus Author ID: https://www.scopus.com/authid/detail.uri?authorId=6508379272
RSCI: https://www.elibrary.ru/author_profile.asp?authorid=166794
ORCID ID: https://orcid.org/0000-0002-1516-437X
Google Scholar: https://scholar.google.ru/citations?user=ZZ7Mav0AAAAJ
Academic degree: Candidate of Biological Sciences
Academic title: No title
Position: Senior Researcher
E-mail: Alexei.Kostygov@zin.ru
Contact phone: ---
Educational background: Master of Science in biology, Saint Petersburg State University, 2002
Dissertations: “Conflict of morphological and molecular phylogenetic approaches in the systematics of trypanosomatids.” (PhD)
Research interests: Diversity, systematics and phylogeny of the flagellates of the family Trypanosomatidae. Life cycles and host-parasite relationships in trypanosomatids. Prokaryotic endosymbionts in protists. RNA viruses in trypanosomatids.
Field studies: 2000 – 2004 White Sea, the Republic of Karelia. 2016 – Hainan island (China).
Pedagogical activity: Current:
  • Special protistological seminar (University of Ostrava)
  • Lectures on molecular phylogenetics
  • Supervision of BSc, MSc and PhD students (University of Ostrava)
Past:
  • Practicum “Molecular biology methods in zoology and ecology” (St. Petersburg State University)
  • Supervision of a MSc student (St. Petersburg State University)
Scientific projects and grants:
  • Russian Foundation for Basic Research, grant 18-04-00138 “Trypanosomatids and their prokaryotic endosymbionts: cophylogeny and diversity of symbiotic associations”
  • Russian Science Foundation grant 18-14-00134 “Development of a phylogenetically coordinated model of evolution of life cycles in parasitic flagellates of the order Trypanosomatida”
  • European Commission Operational Programme for Research, Development and Education “Centre for research of pathogenicity and virulence of parasites” project OPVVV 16_019/0000759
  • Moravskoslezský kraj Research Initiative DT01-021358
  • Grant from the Statutory City of Ostrava 0924/2016/ŠaS
Selected Publications:
  • Maslov D.A., Opperdoes F.R., Kostygov A.Y., Hashimi H., Lukeš J., Yurchenko V. 2019. Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution. Parasitology 146: 1-27. https://doi.org/10.1017/S0031182018000951
  • Frolov, A.O., Malysheva, M.N., Ganyukova, A.I., Yurchenko, V., Kostygov, A.Y. 2018. Obligate development of Blastocrithidia papi (Trypanosomatidae) in the Malpighian tubules of Pyrrhocoris apterus (Hemiptera) and coordination of host-parasite life cycles. PLOS ONE 13: e0204467. https://doi.org/10.1371/journal.pone.0204467
  • Grybchuk, D., Kostygov, A.Y., Macedo, D.H., Votýpka, J., Lukeš, J., Yurchenko, V. 2018. RNA viruses in Blechomonas (Trypanosomatidae) and evolution of Leishmaniavirus. mBio 9: e01932-18. https://doi.org/10.1128/mBio.01932-18
  • Spodareva V.V., Grybchuk-Ieremenko A., Losev A., Votýpka J., Lukeš J., Yurchenko V., Kostygov A.Y. 2018. Diversity and evolution of anuran trypanosomes: insights from the study of European species. Parasites & Vectors. 11: 447. https://doi.org/10.1186/s13071-018-3023-1
  • Silva, F.M., Kostygov, A.Y., Spodareva, V.V., Butenko, A., Tossou, R., Lukeš, J., Yurchenko, V., Alves, J.M.P. 2018. The reduced genome of Candidatus Kinetoplastibacterium sorsogonicusi, the endosymbiont of Kentomonas sorsogonicus (Trypanosomatidae): loss of the heme synthesis pathway. Parasitology 145:1287–1293. https://doi.org/10.1017/S003118201800046X
  • Grybchuk, D., Akopyants. N.S., Kostygov, A.Y., Konovalovas, A., Lye, L.-F., Dobson, D.E., Zangger, H., Fasel. N., Butenko, A., Frolov. A.O., Votýpka, J., d'Avila-Levy, C.M., Kulich, P., Moravcová, J., Plevka, P., Rogozin, I.B., Serva, S., Lukeš, J., Beverley, S.M., Yurchenko, V. 2018. Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. Proceedings of the National Academy of Sciences of USA 115: E506-E515. https://doi.org/10.1073/pnas.1717806115
  • Kostygov, A.Y., Butenko, A, Nenarokova, A., Tashyreva, D., Flegontov, P., Lukeš J., Yurchenko, V. 2017. Genome of Ca. Pandoraea novymonadis, an endosymbiotic bacterium of the trypanosomatid Novymonas esmeraldas. Frontiers in Microbiology 8: 1940.
  • Záhonová, K., Kostygov, A. Y., Ševčíková, T., Yurchenko, V., Eliáš, M. 2016. An unprecedented non-canonical nuclear genetic code with all three termination codons reassigned as sense codons. Current Biology 26: 2364-2369.
  • Kostygov, A.Y., Dobáková, E., Grybchuk-Ieremenko, A., Váhala, D., Maslov, D., Votýpka, J., Lukeš, J., Yurchenko, V. 2016. Novel trypanosomatid – bacterium association: evolution of endosymbiosis in action. mBio 7: e01985-15.
  • Kraeva, N., Butenko, A., Hlaváčová, J., Kostygov, A.Y., Myškova, J., Grybchuk, D., Leštinová, T., Votýpka, J., Volf, P., Opperdoes, F., Flegontov, P., Lukeš, J., Yurchenko, V. 2015. Leptomonas seymouri: adaptations to the dixenous life cycle analyzed by genome sequencing, transcriptome profiling and co-infection with Leishmania donovani. PLOS Pathogens 11: e1005127